There are many different formations that Nike Shox R5 come in, but they usually come with four circular columns in a square formation for maximum cushioning. There can also be five or six Shox that vary in height, and triangular and rectangular Shox that provide better stability. Some shoes have midsoles made entirely of Shox, like the TL series.Based on the information extracted from its predecessor, the section prototype of the Nike Shox R5 line was a scaled down, more stable shoe using a leaf shaped spring to provide the optimal spring of the first unit. Easier on the eyes with good cushioning, it lacked stability and durability.

The Nike Shox R5 running shoe has been the most successful shoe in the Nike Shox R5 lineup. The shoe was available in a variety of colors and was also available on Nike ID. The R4 has been released several times and is the only shoe in the original lineup to have been released several times.The Shox shoes were very cutting edge using a super high density polyurithane hollow foam columns as the shock absorbers in combination with a TPU heel counter to ensure equal distribution of the energy from impact.